Anti-Nav1.8 Na+ Channel Antibody 75-166 from Antibodies Inc.

Product Specs
ItemAnti-Nav1.8 Na+ Channel Antibody
CompanyAntibodies Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number75-166
Antibody TypePrimary Antibody
ClonalityMonoclonal
ReactivityHuman, Mouse, and Rat
Regulatory StatusThese antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans
FormatLiquid, Purified by Protein A chromatography
ApplicationsIHC, ICC, WB, MA
CloneN134/12
Gene NameScn10a Sns
HostMouse
Quantity100 µL
Molecular Weight220 kDa
TargetNav1.8 Na+ channel
IsotypeIgG2a
Conjugate/TagUnconjugated
Brand/TrademarkNeuroMab
ImmunogenFusion protein amino acids 1724-1956 (cytoplasmic C-terminus) of rat Nav1.8 (accession number Q62968) produced recombinantly in E. Coli
ValidationEach new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern
NCBI Gene AliasesNa(V)1.8, Nav1.8, PN3

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Antibodies Inc.

P.O. Box 1560

Davis, CA 95617-1560

United States

Phone: (800) 824-8540

Email: orders@antibodiesinc.com

Company Profile

Website: https://www.antibodiesinc.com/

(1) Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2⁺ DRG sensory neuronsNature neuroscienceFebruary 1, 2022Yang NJ, Isensee J, Neel DV, Quadros AU, Zhang HB, Lauzadis J, Liu SM, Shiers S, Belu A, Palan S, et al.

(2) Prolactin signaling modulates stress-induced behavioral responses in a preclinical mouse model of migraineHeadacheJanuary 1, 2022Mason BN, Kallianpur R, Price TJ, Akopian AN, Dussor GO.

(3) Depolarization induces nociceptor sensitization by CaV1.2-mediated PKA-II activationThe Journal of cell biologyOctober 4, 2021Isensee J, van Cann M, Despang P, Araldi D, Moeller K, Petersen J, Schmidtko A, Matthes J, Levine JD, Hucho T.

(4) MicroRNA-96 is required to prevent allodynia by repressing voltage-gated sodium channels in spinal cordProg NeurobiolJuly 1, 2021Sun L, Xia R, Jiang J, Wen T, Huang Z, Qian R, Zhang MD, Zhou M, Peng C.

(5) Loss-of-function of EBP50 is a new cause of hereditary peripheral neuropathy: EBP50 functions in peripheral nerve systemGliaSeptember 1, 2020Song GJ, Gupta DP, Rahman MH, Park HT, Al Ghouleh I, Bisello A, Lee MG, Park JY, Park HH, Jun JH, et al.

(6) The role of Na_V channels in synaptic transmission after axotomy in a microfluidic culture platformScientific reportsSeptember 9, 2019Vysokov N, McMahon SB, Raouf R.

(7) HCN3 ion channels: roles in sensory neuronal excitability and painThe Journal of physiologySeptember 1, 2019Lainez S, Tsantoulas C, Biel M, McNaughton PA.

(8) Mice lacking Kcns1 in peripheral neurons show increased basal and neuropathic pain sensitivityPainAugust 1, 2018Tsantoulas C, Denk F, Signore M, Nassar MA, Futai K, McMahon SB.

(9) Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during agingJournal of cell scienceJuly 1, 2017Isensee J, Schild C, Schwede F, Hucho T.

(10) Chemogenetic Inhibition of Pain Neurons in a Mouse Model of OsteoarthritisArthritis & RheumatologyJuly 1, 2017Rachel E. Miller, Shingo Ishihara, Bula Bhattacharyya, Ada Delaney, Daniela M. Menichella, Richard J. Miller, Anne-Marie Malfaitsections. DRG sections were stained with the primary antibodies anti-Nav1.8 (Antibodies Incorporated, #75-166; 1:250) and anti-HA tag (Cell Signaling Technology, #3724S; 1:250). Spinal cord sections were stained

(11) A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animalThe Journal of neuroscience : the official journal of the Society for NeuroscienceMay 20, 2015Lu VB, Ikeda SR, Puhl HL 3rd.

(12) Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injuryThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 21, 2015Ritter DM, Zemel BM, Hala TJ, O'Leary ME, Lepore AC, Covarrubias M.

(13) The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor FunctionCell reportsJanuary 20, 2015François A, Schüetter N, Laffray S, Sanguesa J, Pizzoccaro A, Dubel S, Mantilleri A, Nargeot J, Noël J, Wood JN, et al.

(14) Tetrodotoxin-resistant voltage-gated sodium channel Nav 1.8 constitutively interacts with ankyrin GJournal of neurochemistryOctober 1, 2014Montersino A, Brachet A, Ferracci G, Fache MP, Angles d'Ortoli S, Liu W, Rueda-Boroni F, Castets F, Dargent B.

(15) TREK2 expressed selectively in IB4-binding C-fiber nociceptors hyperpolarizes their membrane potentials and limits spontaneous painThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 22, 2014Acosta C, Djouhri L, Watkins R, Berry C, Bromage K, Lawson SN.

(16) A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neuronsNature neuroscienceAugust 1, 2013Zhao X, Tang Z, Zhang H, Atianjoh FE, Zhao JY, Liang L, Wang W, Guan X, Kao SC, Tiwari V, et al.

(17) Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold painThe Journal of neuroscience : the official journal of the Society for NeuroscienceJuly 24, 2013Lippoldt EK, Elmes RR, McCoy DD, Knowlton WM, McKemy DD.

(18) Protein kinase B/Akt is required for complete Freund's adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neuronsThe journal of pain : official journal of the American Pain SocietyJune 1, 2013Liang L, Fan L, Tao B, Yaster M, Tao YX.

(19) A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesiaThe Journal of neuroscience : the official journal of the Society for NeuroscienceFebruary 13, 2013Knowlton WM, Palkar R, Lippoldt EK, McCoy DD, Baluch F, Chen J, McKemy DD.

(20) Probing functional properties of nociceptive axons using a microfluidic culture systemPloS oneJanuary 1, 2013Tsantoulas C, Farmer C, Machado P, Baba K, McMahon SB, Raouf R.

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Anti-Nav1.8 Na+ Channel Antibody from Antibodies Inc.

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Anti-Nav1.8 Na+ Channel Antibody from Antibodies Inc.

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